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EDITORIAL: A Small Molecule for a Large Disease
Mercredi 25 Juin 2008 - 06:55 - 6 mois, 2 semaines depuis - 8 lectures - Presse spécialisée - New England Journal of Medicin Almost three decades ago, Victor McKusick and I reviewed Marfan's syndrome in the Journal and advised traditional medical and surgical approaches to management.1 The holy grail at that time was ... |
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Espèces menacées, danger sous-estimé
Vendredi 04 Juillet 2008 - 04:45 - 6 mois, 1 semaine depuis - 8 lectures - Presse généraliste - Nouvel Observateur Sciences Le risque de voir disparaître certaines espèces est cent fois plus élevé que ce que les estimations actuelles laissent paraitre, affirment deux chercheurs. |
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Peignons les toitures en blanc pour contrer le réchauffement climatique
Jeudi 25 Septembre 2008 - 05:16 - 3 mois, 2 semaines depuis - 8 lectures - Presse généraliste - Le monde Sciences L'effet est connu : les couleurs claires réfléchissent plus de rayonnement solaire que les teintes sombres. |
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Les oiseaux sacrifiés du pétrole
Mercredi 03 Décembre 2008 - 10:56 - 1 mois depuis - 8 lectures - Presse généraliste - Nouvel Observateur Sciences Au Canada, l’exploitation des sables bitumineux par l’industrie pétrolière menace la survie de millions d’oiseaux migrateurs faisant escale dans ces régions semi-nordiques. |
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SOUNDING BOARD: Informing Candidates for Solid-Organ Transplantation about Donor Risk Factors
Mercredi 25 Juin 2008 - 06:55 - 6 mois, 2 semaines depuis - 8 lectures - Presse spécialisée - New England Journal of Medicin A debate exists about informing potential organ-transplant recipients about the general risks associated with transplantation and the specific risks associated with a particular organ. In this article, the authors discuss whether and how the behavioral risks of donors should be considered and how that might affect choices and outcomes. |
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ORIGINAL ARTICLE: K-ras Mutations and Benefit from Cetuximab in Advanced Colorectal Cancer
Mercredi 22 Octobre 2008 - 06:55 - 2 mois, 2 semaines depuis - 8 lectures - Presse spécialisée - New England Journal of Medicin This study examined the mutation status of the K-ras gene in colorectal tumors from patients who were enrolled in a trial of cetuximab, a monoclonal antibody against the epidermal growth factor receptor (EGFR). A survival benefit was found among patients with tumors bearing wild-type K-ras but not among patients with tumors bearing mutated K-ras. Wild-type K-ras is essential in transmitting signals initiated by EGFR. |
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CORRESPONDENCE: Case-Control Study of Smoking and Death in India
Mercredi 25 Juin 2008 - 06:55 - 6 mois, 2 semaines depuis - 8 lectures - Presse spécialisée - New England Journal of Medicin To the Editor: The article by Jha et al. (March 13 issue)1 on the large and growing number of deaths ... |
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Disease Burden Related to Chronic HCV Infection (Slides With Transcript)
Lundi 22 Septembre 2008 - 07:47 - 3 mois, 2 semaines depuis - 8 lectures - Presse spécialisée - Medscape family medicine |
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ORIGINAL ARTICLE: Toll-like Receptor 4 Polymorphisms and Aspergillosis in Stem-Cell Transplantation
Mercredi 22 Octobre 2008 - 06:55 - 2 mois, 2 semaines depuis - 8 lectures - Presse spécialisée - New England Journal of Medicin Toll-like receptors (TLRs) are a central aspect of the innate immune response. Different TLRs are associated with the immune response to different infectious pathogens. In this retrospective analysis, an increased susceptibility to invasive aspergillosis was associated with certain polymorphisms in donor TLR4 in patients who received an allogeneic hematopoietic stem-cell transplant from an unrelated donor. |
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ORIGINAL ARTICLE: Pulmonary-Vein Isolation for Atrial Fibrillation in Patients with Heart Failure
Mercredi 22 Octobre 2008 - 06:55 - 2 mois, 2 semaines depuis - 8 lectures - Presse spécialisée - New England Journal of Medicin In patients with symptomatic atrial fibrillation and heart failure, pulmonary-vein isolation was found to be superior to atrioventricular-node ablation with biventricular pacing. Isolation of the pulmonary veins by means of ablation is a viable option for patients with refractory atrial fibrillation and heart failure. |
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