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New England Journal of Medicin - Objets Actus

PERSPECTIVE: Home Delivery -- Bringing Primary Care to the Housebound Elderly
Mercredi 03 Décembre 2008 - 06:55 - 1 mois depuis - Presse spécialisée - New England Journal of Medicin
Nurse practitioner Gail Metcalf toted her medical bag up the steep stairway of a triple-decker house in Dorchester, a low-income neighborhood of Boston, and greeted her patient, Mrs. E, a ...

PERSPECTIVE: Circumcision -- A Surgical Strategy for HIV Prevention in Africa
Mercredi 03 Décembre 2008 - 06:55 - 1 mois depuis - Presse spécialisée - New England Journal of Medicin
In a radical departure from earlier strategies, public health officials are now arguing that circumcision of men should be a key weapon in the fight against infection with the human ...

ORIGINAL ARTICLE: Benazepril plus Amlodipine or Hydrochlorothiazide for Hypertension in High-Risk Patients
Mercredi 03 Décembre 2008 - 06:55 - 1 mois depuis - Presse spécialisée - New England Journal of Medicin
The optimal combination drug therapy for treatment of hypertension is not established, although current U.S. guidelines recommend inclusion of a diuretic. This double-blind trial, in which high-risk patients with hypertension were randomly assigned to treatment with benazepril plus either amlodipine or hydrochlorothiazide, showed that benazepril plus amlodipine was superior to benazepril plus hydrochlorothiazide in reducing cardiovascular events in this population.

ORIGINAL ARTICLE: Prolonged Therapy of Advanced Chronic Hepatitis C with Low-Dose Peginterferon
Mercredi 03 Décembre 2008 - 06:55 - 1 mois depuis - Presse spécialisée - New England Journal of Medicin
Patients with chronic hepatitis C who did not have a sustained viral response to peginterferon and ribavirin were randomly assigned to receive low-dose peginterferon or no treatment for 3.5 years. The clinical and histologic outcomes were not better in patients treated with peginterferon. These findings do not support the use of long-term peginterferon in patients who do not have a sustained virologic response to initial therapy.

ORIGINAL ARTICLE: Tenofovir Disoproxil Fumarate versus Adefovir Dipivoxil for Chronic Hepatitis B
Mercredi 03 Décembre 2008 - 06:55 - 1 mois depuis - Presse spécialisée - New England Journal of Medicin
In this randomized comparison of treatment with tenofovir disoproxil fumarate or adefovir dipivoxil for 48 weeks in patients with chronic hepatitis B, tenofovir was more likely to result in viral suppression. The follow-up period was not long enough to assess the resistance patterns, risks, and benefits of long-term treatment.

ORIGINAL ARTICLE: Irbesartan in Patients with Heart Failure and Preserved Ejection Fraction
Mercredi 03 Décembre 2008 - 06:55 - 1 mois depuis - Presse spécialisée - New England Journal of Medicin
In a multicenter trial, 4128 patients who had heart failure with a preserved ejection fraction were randomly assigned to receive irbesartan or placebo and were followed for a mean of 49.5 months. There were no significant differences between the two study groups in the rate of the primary outcome (death or hospitalization for heart failure).

CLINICAL THERAPEUTICS: Levodopa for the Treatment of Parkinson's Disease
Mercredi 03 Décembre 2008 - 06:55 - 1 mois depuis - Presse spécialisée - New England Journal of Medicin
A 62-year-old man presents with Parkinson's disease, and treatment with levodopa is recommended. Levodopa, a naturally occurring amino acid that is metabolized to dopamine in the brain, is considered the most effective drug available for Parkinson's disease. However, after several years of therapy, serious side effects, including motor fluctuations and dyskinesias, may occur.

IMAGES IN CLINICAL MEDICINE: Acute Calcific Tendinitis
Mercredi 03 Décembre 2008 - 06:55 - 1 mois depuis - Presse spécialisée - New England Journal of Medicin
A 56-year-old woman presented to the emergency department with a 3-day history of severe pain in and loss of movement of her right index finger. She reported that for the ...

IMAGES IN CLINICAL MEDICINE: Central Pontine Myelinolysis
Mercredi 03 Décembre 2008 - 06:55 - 1 mois depuis - Presse spécialisée - New England Journal of Medicin
A 26-year-old man with a history of chronic alcohol abuse presented with dysarthria, lethargy, and horizontal nystagmus. Results of a clinical examination and blood tests were otherwise normal, including a ...

CLINICAL PROBLEM-SOLVING: Taken Out of Context
Mercredi 03 Décembre 2008 - 06:55 - 1 mois depuis - Presse spécialisée - New England Journal of Medicin
A 25-year-old woman with a history of depression, mitral-valve prolapse, and migraine headaches presented to a hospital emergency department with a 3-day history of subjective fever, diffuse arthralgia, and a severe generalized headache that was not characteristic of her previous migraines.

Actus fournies par : New England Journal of Medicine

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